Migraine is a disease of the nervous system characterized by severe headache. The headache is so pronounced that it forces a person to stop all activities, to hide from the outside world. Women more often than men, suffer from migraine. Family history is one of the most common risk factors for migraine. A headache attack with migraine can last for hours and days without interruption, causing the patient to suffer unbearably. People can avoid headaches with migraines using a variety of pain relief drugs. Medication for migraine is a rather difficult task. There are hundreds of trade names for migraine medications, most often, these medications are aimed at stopping the pain syndrome, but there are general drugs that prevent the recurrence of pain attacks, and also reduce the intensity of the pain syndrome in principle. For stopping the attack the group can include almost all existing analgesics. Proved effectiveness has non-steroidal anti-inflammatory drugs (Diclofenac, Celebrex medication etc.). A wide distribution was found in preparation Cafergot containing ergotamine, including in combination with caffeine.
Cafergot migraine medicine is a combined drug and its effect is developed due to the properties of its constituent components. Caffeine has a stimulating effect on the central nervous system, mainly on the cerebral cortex, vasomotor and respiratory centers, which increases physical and mental performance, reduces fatigue and drowsiness. Also, caffeine increases the frequency and strength of heartbeats, increasing blood pressure with hypotension. Ergotamine has a vasoconstrictive effect, its absorption is enhanced by caffeine. Caffeine, when taken orally, is quickly and almost completely absorbed. Connection with plasma proteins is 35%. It is almost completely metabolized. Excretion occurs mainly with urine. When ingesting ergotamine, 62% of the substance is absorbed from the gastrointestinal tract. Within 2 hours its maximum plasma concentration is reached. The connection with plasma proteins is 98%.
What is main application of Cafergot?
You order Cafergot online for acute migraine attacks and similar attacks of headaches of vascular genesis.
Do not buy Cafergot if you have:
-panic anxiety disorders, agoraphobia; sleep disorders;
-organic diseases of the cardiovascular system (acute myocardial infarction, severe atherosclerosis, angina pectoris, paroxysmal tachycardia, frequent ventricular extrasystole);
-increased sensitivity to one of the components of the drug;
-violation of peripheral circulation;
-obliterating vascular diseases;
-severe arterial hypertension;
-hepatic or renal insufficiency;
Cafergot in pregnancy and lactation is forbidden. If symptoms such as numbness of the fingertips of the hands or feet appear, stop taking the medication immediately and consult a doctor. Preparation is used to treat an acute migraine attack, it should not be used to prevent seizures or take often for a long time. People should not use Cafergot and alcohol together.
Instructions for the use of Cafergot: dosage
Medicament should be taken at the very beginning of an attack. For the first dose, a dosage of 2 tablets is recommended. If after 30 minutes, there is no improvement in the condition, one more tablet should be taken. Reception of the drug can be repeated and further with an interval of 30 minutes, not exceeding the maximum daily dose. In subsequent attacks, the initial Cafergot dosage can be increased to 3 tablets, depending on the total dose taken during previous attacks. The maximum daily dose is 6 mg. If you are prescribed different NSAIDs, it is possible to learn the information about dosage of Aleve, Celebrex reviews, Diclofenac and many others online.
What are undesirable effects during Cafergot intake?
Medication Cafergot side effects are various:
-CNS: anxiety, agitation, tremor, dizziness, headache, paresthesia in the extremities, cramps, reflex intensification, tachypnea, insomnia;
-cardiovascular system: tachycardia, palpitation, cardialgia, increased blood pressure;
-gastrointestinal tract: diarrhea, nausea, vomiting; allergic reactions: itching, swelling.
Prolonged use of preparation may lead to Cafergot addiction symptoms, drug dependence, weakness in the legs, myalgia.
Overdose and special information
Symptoms of an overdose can be nausea, vomiting, numbness of fingers and toes, retardation, drowsiness, epileptic seizures, stupor, coma. Patients are recommended symptomatic therapy. Sudden abolition of the medicine may lead to increased inhibition of the central nervous system, increased drowsiness and fatigue.